Tag Archives: Tranexamic Acid

2A, 2B: Tranexamic Acid and CRASH-II

Practice Change: If Tranexamic Acid is not on your short list of life saving medications in trauma, it should be!  It is inexpensive and has a mortality benefit in hemorrhaging trauma with a NNT of 67 to save a life.   … Continue reading

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2C. TXA in Head Injury?

What About Use In Head Injuries? Take Home: Our system’s trauma protocol suggests stopping TXA once there is a head injury discovered, BUT given this data, I wouldn’t be too worried that we had caused harm in the patient by … Continue reading

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2D. TXA in Mature Trauma System

Take Home: TXA works in an established trauma system. – Annals of Surgery 2015 Study: Prospective Observational Cohort done in England of patients while their trauma system initiated use of TXA therapy in their Massive Transfusion Protocols Patients: Trauma patients … Continue reading

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2E. Military TXA Studies – TXA looks good in multiple settings.

Military Studies  Take Home: TXA seems effective in multiple settings and multiple studies. There are several other studies evaluating TXA in a military setting. TXA does seem effective in these studies as well, but because the protocols are different and they … Continue reading

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